Skip to content


    Side Effects

    List Acitretin side effects by likelihood and severity.

    The following side effects are associated with acitretin:

    Common side effects of acitretin:

    • Abnormal Increase In Muscle ToneSevere
    • Feel Like Throwing UpSevere
    • Head PainSevere
    • Increase In The Size Of Vertebrae Or Bones Of The SpineSevere
    • Joint PainSevere
    • Muscle PainSevere
    • Throwing UpSevere
    • Abnormal Liver Function TestsLess Severe
    • Chapped LipsLess Severe
    • Combined High Blood Cholesterol And Triglyceride LevelLess Severe
    • Dry EyeLess Severe
    • Dryness Of The NoseLess Severe
    • Excessive ThirstLess Severe
    • Hair LossLess Severe
    • Increased Wax In The EarsLess Severe
    • Inflammation Of The GumsLess Severe
    • Inflammation Of The NoseLess Severe
    • Inflammation Of The Skin Of The EyelidLess Severe
    • ItchingLess Severe
    • Painful, Red Or Swollen MouthLess Severe
    • Peeling Of The Skin Of The FeetLess Severe
    • Peeling Of The Skin Of The HandsLess Severe
    • Sun-Sensitive SkinLess Severe

    Infrequent side effects of acitretin:

    • Accumulation Of Fluid In The Tissues Of The EyelidSevere
    • Blurred VisionSevere
    • ChillsSevere
    • Excessive Watery EyesSevere
    • Eye IrritationSevere
    • Inflammation And Infection Of Nail CuticleSevere
    • Inflammation Of The EyelidSevere
    • Numbness And TinglingSevere
    • Pain In The EyeSevere
    • Pink EyeSevere
    • Problems With EyesightSevere
    • Red EyesSevere
    • Sensitive To LightSevere
    • Canker SoreLess Severe
    • ConstipationLess Severe
    • DiarrheaLess Severe
    • Excessive SweatingLess Severe
    • Fingernail And/Or Toenail DiseaseLess Severe
    • Low EnergyLess Severe
    • NosebleedLess Severe

    Rare side effects of acitretin:

    • A Groove In The SkinSevere
    • Acute Inflammation Of The PancreasSevere
    • CataractsSevere
    • Decreased Vision At NightSevere
    • Erosion Of The Cornea Of The EyeSevere
    • Flu-Like SymptomsSevere
    • Giant HivesSevere
    • Having Thoughts Of SuicideSevere
    • Heart AttackSevere
    • HepatitisSevere
    • InfectionSevere
    • Inflammation Of Skin Caused By An AllergySevere
    • Inflammation Of The External Ear Resembling EczemaSevere
    • Inflammation Of The Voice BoxSevere
    • Inflammation Or Infection Of Vagina And VulvaSevere
    • Large Purple Or Brown Skin BlotchesSevere
    • Muscle ProblemsSevere
    • Nodular Inflammatory Skin Lesions With Production Of PusSevere
    • Obstruction Of A Blood Vessel By A Blood ClotSevere
    • Plasma Fluid & Proteins Leaking Outside Of CapillariesSevere
    • Pseudotumor CerebriSevere
    • Psoriasiform EruptionSevere
    • Skin Rash With SloughingSevere
    • Skin UlcerSevere
    • StrokeSevere
    • StyeSevere
    • Throat IrritationSevere
    • Yellowing Of Skin Or Eyes From Liver ProblemsSevere
    • Aggressive BehaviorLess Severe
    • High Blood SugarLess Severe
    • HivesLess Severe
    • Increased Feeling Of The SkinLess Severe
    • Reduced Eyelash GrowthLess Severe
    • Thin Fragile SkinLess Severe

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

    More about Drugs and Medications

    URAC Seal TRUSTe Privacy Certification TAG Registered Seal HONcode Seal AdChoices