Selected Nephrotoxic Agents/Immune Globulin IV (IGIV) Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Both of your medicines may damage your kidneys.

What might happen:

Taking these medicines together may increase the risk of damage to your kidneys.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know right away that you are using these medicines together. Your doctor may want to change one of your medicines. Be sure to keep all laboratory appointments and let your doctor know if you notice a change in amount of urine you are making.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Bivigam (human immunoglobulin g injection) US prescribing information. Biotest Pharmaceuticals Corporation May, 2015.
  • 2.Gammagard S/D (human immunoglobulin g) US prescribing information. Baxter Healthcare Corporation June, 2011.
  • 3.Carimune Nanofiltered (human immunoglobulin g injction, powder, lyophilized) US prescribing information. CSL Behring AG November, 2016.
  • 4.USFood and Drug Administration. MMWR Weekly: Renal Insufficiency and Failure Associated with Immune Globulin Intravenous Therapy -- United States, 1985-1998. Available at: https://www.cdc.gov/mmwr/preview/mmwrhtml/mm4824a3.htm June 25, 1999.