Skip to content

Medical Dictionary

ankylosing spondylitis

  1. arthritis of the spine, resembling rheumatoid arthritis, which may progress to bony ankylosis with ossification of the anterior and posterior longitudinal ligaments; the disease is more common in males, often with the rheumatoid factor absent and the HLA antigen present. There is a striking association with the B27 tissue type and the strong familial aggregation suggests an important genetic factor, perhaps inherited as an autosomal dominant [MIM*106300]; the mechanism, however, remains obscure.

Syn: Marie-Strümpell disease, rheumatoid spondylitis, Strümpell-Marie disease

WebMD Medical Reference from "Stedman's Medical Dictionary"

The publisher is not responsible (as a matter of product liability, negligence or otherwise) for any injury resulting from any material contained herein. This publication contains information relating to general principles of medical care which should not be construed as specific instructions for individual patients. Manufacturers’ product information and package inserts should be reviewed for current information, including contraindications, dosages and precautions.

Hot Topics

Health Solutions From Our Sponsors

WebMD Video: Now Playing

Click here to wach video: Dirty Truth About Hand Washing

Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

Click here to watch video: Dirty Truth About Hand Washing

Popular Slideshows & Tools on WebMD

bloodstream
Tips to help prevent clots.
checking blood sugar
Symptoms, diagnosis and treatment.
acupuncture needle on shoulder
Live and thrive.
gloved hand holding syringe
10 preventable diseases.
lone star tick
How to identify that bite.
man eating meal
Folates, green tea and more.
brain scan with soda
Tips to avoid complications.
disciplining a boy
Types, symptoms, causes.
Woman with stressed, fatigue
Get relief tips.
restroom sign
Food and drinks that make you go.
two male hands
Understanding RA.

Women's Health Newsletter

Find out what women really need.