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3.5 Overall Rating

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Most voted positive review

13 People found this comment helpful

I was prescribed protriptyline to help with chronic daily headaches I was having. I started off taking one 5mg tablet but quickly increased to 20mg because the side effects were minimal. On this dose, I had pretty significant dry mouth, and I was unable to fall asleep at night without taking another medication to help with sleep (this drug is a stimulant). I also noticed a somewhat decreased ap...

Most voted negative review

4 People found this comment helpful

I have taken this medication for a week now in conjunction to assist my sleepless-ness. However, I had adverse affects of severe sadness and depression, I could not sleep on this medication and have been very unstable in my mood. I have had to stop taking this medication due to waking up in a full on crying fit for no reason.

Shared reviews and ratings

Laurie | Female | Patient
6/13/2023
Condition: Depression
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I was hospitalized insect pediatric board 1991 from a depressive major event doctor tried this medicine for me and in 4 days normal completely relief from depression and side effects are dry mouth but it's worth the relief is worth it

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Anonymous | 45-54 | Female | On medication for less than 1 month | Patient
10/25/2017
Condition: Other
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

Allergic to orange pills

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Anonymous | 55-64 | Female | On medication for 1 to 6 months | Patient
2/16/2016
Condition: Depression
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

headaches aches pains irrability

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Sleeepy | 35-44 | Male | On medication for 1 to 6 months | Patient
4/9/2012
Condition: Other
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

I have autoimmune disease and extreme fatigue. Started taking this in hopes that it's mild stimulating action would help (I cant handle a real stimulant, I pay dearly if I take one). This has made me more awake, but unfortunately starting around 6pm. I need that 'little more awake' feeling at 6am! No complaints about side effects, maybe I just need to tweak the times I take this (like wake myself in the night) ;)

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Anonymous | 19-24 | Female | On medication for 1 to 6 months | Patient
6/3/2011
Condition: Other
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

I was prescribed protriptyline to help with chronic daily headaches I was having. I started off taking one 5mg tablet but quickly increased to 20mg because the side effects were minimal. On this dose, I had pretty significant dry mouth, and I was unable to fall asleep at night without taking another medication to help with sleep (this drug is a stimulant). I also noticed a somewhat decreased appetite. As far as effectiveness, this drug definitely helped with my headaches. Within 2 weeks, I saw a decrease in the severity of the headaches and I had more days headache-free each month (before taking the drug I was having about 5 headache free days a month). However, the effect wasn't drastic and I continued to try other things to further decrease my headaches. Read More Read Less

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CG | 35-44 | Female | On medication for 2 to less than 5 years | Patient
11/8/2010
Condition: Other
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

I take this to prevent headaches (mixed migraine-tension headache symptoms). I've tried half a dozen other treatments and this is the first one that works. My headaches are down to 1/week, vs 4-5/wk, and are therefore fairly manageable. The only annoying side effect is dry mouth (I chew gum all the time). Also, when I had dental work done novocaine didn't work so my dentist told me to stop taking Vivactil and come back in 2 weeks.

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Anonymous | 35-44 | Female | On medication for 1 to 6 months | Patient
6/22/2010
Condition: Other
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I am using this drug as a migraine preventitive and it is GREAT. I have not had a migraine in 6 weeks and was having 2-5 a week. Have tried so many other drugs that did not work. I am so happy with this drug.

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DBERRY | 25-34 | Female | On medication for less than 1 month | Patient
3/11/2010
Condition: Other
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I have taken this medication for a week now in conjunction to assist my sleepless-ness. However, I had adverse affects of severe sadness and depression, I could not sleep on this medication and have been very unstable in my mood. I have had to stop taking this medication due to waking up in a full on crying fit for no reason.

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Anonymous | 55-64 | Male | On medication for less than 1 month | Patient
9/19/2009
Condition: Generalized Attack of Muscular Weakness
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

Never did a thing..This is my third try at this. This site does not let me make a negitive response. This is my 3rd attempt.

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