Skip to content

    Read user comments about the side effects, benefits, and effectiveness of Depakote oral.

    Overall User Ratings

    708 Total User Reviews

    User Reviews

    1-5 of 224 Next»
    Condition: Bipolar Depression
    5/19/2016 10:30:36 AM

    Reviewer: Rich74, 35-44 Male on Treatment for 10 years or more (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 4

    Satisfaction

    Current Rating: 5

    Comment:
    Depakote is my main medication to treat my Bi-polar Disorder. It has really worked for me; manages my mood swings well; and I don't experience any side-effects from it. My only complaint is that I have 2 get regular lab work to monitor my liver enzymes. I have been on it for 20 yrs and my liver is normal.

    Condition: Bipolar Depression
    8/3/2015 7:42:36 AM

    Reviewer: JC, 45-54 Male on Treatment for 2 to less than 5 years (Patient)

    Effectiveness

    Current Rating: 1

    Ease of Use

    Current Rating: 1

    Satisfaction

    Current Rating: 1

    Comment:
    First prescribed for me after failed trials with Lamictal, this drug had zero efficacy as well, even on ridiculously high dosages of 2000mg per day. I indeed have disabling depression and anxiety and RARE pronounced mood swings. I've had terrible side effects personally, from weight yoyo'ing to hair loss to water retention, peripheral edema, and signs of renal failure. Hoping this review h ... Show Full Comment

    Condition: Bipolar Depression
    5/11/2015 3:42:30 PM

    Reviewer: j, 55-64 Male on Treatment for 2 to less than 5 years (Patient)

    Effectiveness

    Current Rating: 3

    Ease of Use

    Current Rating: 3

    Satisfaction

    Current Rating: 2

    Comment:
    After being on this medication for years. I started to have issue with my liver and pancreas. It got really bad. thought my liver was failing. after 4 weeks in and out of hospital. Levels finally going down. but they took me off of the Depakote

    Condition: Bipolar Depression
    3/26/2015 4:09:50 PM

    Reviewer: jones, 45-54 Male on Treatment for 1 to 6 months (Patient)

    Effectiveness

    Current Rating: 2

    Ease of Use

    Current Rating: 2

    Satisfaction

    Current Rating: 1

    Comment:
    Increased depression, low energy, lots of body pains, confusion, headaches

    Condition: Bipolar Depression
    7/26/2014 10:39:01 PM

    Reviewer: 65-74 Female on Treatment for 6 months to less than 1 year (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:

    1-5 of 224 Next»

    Ask the pharmacist

    Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
    See the Ask the Pharmacist event schedule.

    Ask a Question

    Popular Slideshows & Tools on WebMD

    disciplining a boy
    Types, symptoms, causes.
    fruit drinks
    Eat these to think better.
    embarrassed woman
    Do you feel guilty after eating?
    diabetes supply kit
    Pack and prepare.
    Balding man in mirror
    Treatments & solutions.
    birth control pills
    Which kind is right for you?
    Remember your finger
    Are you getting more forgetful?
    sticky notes on face
    10 tips to clear your brain fog.
    Close up of eye
    12 reasons you're distracted.
    woman biting a big ice cube
    Habits that wreck your teeth.
    apple slices with peanut butter
    What goes best with workouts?
    Pink badge on woman chest to support breat cancer
    Myths and facts.

    Newsletters

    Subscribe to free WebMD newsletters.

    • WebMD Daily

      WebMD Daily

      Subscribe to the WebMD Daily, and you'll get today's top health news and trending topics, and the latest and best information from WebMD.

    • Men's Health

      Men's Health

      Subscribe to the Men's Health newsletter for the latest on disease prevention, fitness, sex, nutrition, and more from WebMD.

    • Women's Health

      Women's Health

      Subscribe to the Women's Health newsletter for the latest on disease prevention, fitness, sex, diet, anti-aging, and more from WebMD.

    By clicking Submit, I agree to the WebMD Terms & Conditions & Privacy Policy and understand that I may opt out of WebMD subscriptions at any time.

    WebMD the app

    Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

    Find Out More
    IMPORTANT: About This Section and Other User-Generated Content on WebMD

    The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

    Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.