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2.5 Overall Rating

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Most voted positive review

137 People found this comment helpful

DO not listen to the other posters here who are most likely making stuff up trying to scare you. My sister is a physician and she went over all the side effects with me. The only real concern is a rash since Prolia does NOT go through the kidney or liver like all the other drugs. This is by FAR the SAFEST osteoporosis medicine. And its the easiest too. When looking at the side effects also look at...

Most voted negative review

17 People found this comment helpful

Pain worse than I've ever had, skin aged and leathery, constipation and can't breathe. I'm in worse shape now than before I had prolia--will NOT take any more. Stomach and digestion problems all the time, can't sleep. 6 months of hell for me. Cholesterol went way up. RA got worse--Dr. said it would help it--a lie! Dr. treated me as a guinea pig--used a sample she had in office--did NOT charge...

Shared reviews and ratings

Kay | 65-74 | Female | On medication for 1 to 6 months | Patient
3/6/2024
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I was prescribed Prolia in Dec., 2023. I've not felt myself since then. Continued muscle pain particularly at injection site with SEVERE muscle and joint pain in shoulder, neck, hips, legs, just about all over. I'm using a heating pad for these symptoms that are keeping me awake at night. I recognize I am at risk of fracture due to loss of bone density, even after taking Tymlos and Fosomax for a number of years and continuing loss of bone density. I will not continue with Prolia. I too recognize these aches and pains may continue the entire time while on Prolia. I'll give it some time. Taking this medication has really made me feel aged!! Read More Read Less

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Deborah | 55-64 | Female | On medication for 1 to less than 2 years | Patient
1/23/2024
Condition: Osteoporosis
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

Prolia made 3 molars shatter. My teeth felt like rubber. After being off of Prolia for about 8 months my teeth felt back to their usual strong bones.eanwhile my smile, facial shape , comfort and oral health has been compromised. I am sorry I ever took this drug.

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Jane French | 75 or over | Female | On medication for 2 to less than 5 years | Patient
1/19/2024
Condition: Osteoporosis
Overall rating 2.3
Effectiveness
Ease of Use
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I deal only in the facts. I have no intention of scaring anyone. I had five doses of PROLIA and this gave me back-to-back UTIs, Cellulitis, pelvic pain and pain (similar to muscle spasms) at the top of my legs when resting. I have stopped taking PROLIA. All of these adverse effects have gone away. These are the facts. Make of them what you will.

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Anonymous | 65-74 | Female | On medication for 1 to less than 2 years | Patient
1/3/2024
Condition: Osteoporosis
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

I have taken polia 3 time. Every 6 months. I had a dexi scan before starting and after 3 shots. The osteoporosis is worse. I am 67 years old.

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di | 65-74 | Female | On medication for 1 to less than 2 years | Patient
12/21/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

Like most people, I was not advised that once you start Prolia, you can't discontinue easily. You have to go on a complex relay protocol involving an alternative antiresorptive and monitoring of bone turnover (not density - turnover!) We are not warned about this, although it's mentioned in the manufacturer's consumer materials, AND discussed extensively in clinical studies worldwide. The consequences of failing to go on a relay protocol (which is NOT always available) is that you go into "Rebound", that is, accelerated bone turnover which causes catastrophic bone loss AND an increased risk of multiple spontaneous vertebral fractures. This shocking aftereffect of Prolia was not discussed with me and when I discontinued (there are MANY reasons one might discontinue, or miss a shot; I won't get into them here) I did indeed suffer major bone loss AND five spontaneous vertebral fractures, all in one day. That we are not warned that we can get TRAPPED on this drug is the manufacturer's dirty little secret, which it semi-hides from users. There is SO much to know about denosumab - that it doesn't "build" or "strengthen" bone (it only builds density, which comprises undisposed of dead bone cells); that it does NOT "prevent fractures" (merely reduces fracture occurrence in clinical studies); that it cannot be safely discontinued without that complex relay protocol; that it has significant side effects over long term use. There is a Facebook group with more than 11,000 members that has significant science-based information which is worthwhile joining for a summary of the main issues with this appalling drug (Denosumab Side Effects/effets secondaires and support it's called). If your doctor hasn't told you about the Rebound Effect, find one who has, before you even CONSIDER treatment with this drug. He might know how to get you onto the drug but if he doesn't know how to get you OFF of it again, well, you need a new doctor.Read More Read Less

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Trixy | 55-64 | Female | On medication for 1 to 6 months | Patient
12/21/2023
Condition: Osteoporosis
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I had a myriad of horrible side effects. FOR EVERYONE COMMENTING: you cannot just stop this drug. When you do you suffer catastrophic bone loss which can result in Multiple Spontaneous Vertebrae Fractures. You MUST take a bisphosphonate to stop this from happening. Even the drug manufacturer warns of this but many doctors are not informing patients. Join the Prolia Denosumab) Side Effects support Facebook page for more information and help.

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Kay | 75 or over | Female | On medication for 2 to less than 5 years | Patient
12/8/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I just got my 4th Prolia injection and have had absolutely no issues. I am 75 years old and my osteoporosis is pretty bad. I obsessed for months before starting because I have a mouth full of implants and bone grafts in my mouth. I lost my upper teeth when I was 18 and am holding on to my lower implants for dear life. My dentist has told me if I lose the implants, I don’t have enough bone for lower dentures. So I read all the reviews and talked with my dentist. He said I was fine with taking Prolia since my dental hygiene is something I take very seriously. I will be getting my first Dexascan in February since starting Prolia. I am so looking forward to either stabilizing my scores or even better, improving them!Read More Read Less

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Yvonne H | 75 or over | Female | On medication for 1 to 6 months | Patient
10/20/2023
Condition: Decreased Bone Mass Following Menopause
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

A nightmare for me getting the Prolia injection, pain throughout my body like I've never had before. Now after 4 months, have all these varicose veins appearing on my buttocks and quite painful when I'm sitting. Worse decision of my life being talked into having Prolia injection.

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ELENI CHRISTOU | 75 or over | Female | On medication for 1 to 6 months | Patient
10/10/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

I had a serious traumatic brain injury in the past and thankfully after rehabilitation I walked and lived independently. Four months after taking the Prolia injection, it was like all of a sudden the connections between my brain and my legs were lost. I had a problem with standing from the chair, initiating walking and lost my ability to walk and live independently. My advise is to stay away from Prolia if you had a serious traumatic brain injury in the past because in my opinion it negatively affects the human nervous systrem.Read More Read Less

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Kimkim | 55-64 | Female | Patient
9/20/2023
Condition: Other
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

Has anyone experienced high blood pressure using prolia? I have had second injection and have had high pressure. Concerned ??

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Horrified | 65-74 | Female | On medication for less than 1 month |
9/17/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

Never ever again. This drug made me feel like I was poisoned.

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W | 65-74 | Female | On medication for 1 to 6 months | Patient
8/11/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

Two months after my second injection I experienced joint weakness and pain in hips, knees, ankles, and it got progressively worse until I was using a cane and unable to live my normal life. The pain was worse in my right hip and I was scheduled for total hip replacement surgery. My rheumatologist and orthopedist said it was unrelated to the Prolia. However, as it got closer to when I was due for my next injection and the Prolia was getting out of my system, I got better. Soon I wasn’t using the cane, had reduction in pain and was walking normally. I do have osteoarthritis in my hips, but the pain is controlled on Meloxicam and my surgery has been cancelled. Luckily I had to wait for 6 weeks for the surgery, or I would have had it done when I really didn’t need it yet. It is frustrating to tell your doctors what happened to you and be told it isn’t valid. I know my experience with Prolia was a negative one. Read More Read Less

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Valentina Gill | Female | On medication for 2 to less than 5 years | Patient
8/7/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 2.0
Effectiveness
Ease of Use
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I had a fall in 2011 and broke my elbow. I believe that was the beginning of osteoporosis when I was 57. Shortly after, I asked my gynecologist to have a bone density test done, but she said it is unnecessary, and because insurance will not approve, I would be paying for it myself. 3 years later, I was diagnosed with fully blown osteoporosis by the same doctor!!! I was scared and did not know what to do. She suggested Prolia as one of the best treatment options for me. I checked and debated pros and cons, and started taking the injection of 60 mg twice a year. At first, I had jaw pain after the shot, but as it came to year 5 of using the drug, I have developed severe jaw pain, lost several teeth and it continues to destroy my oral health... In addition, I have hip, back and knee pain! I DO NOT RECOMMEND THIS TREATMENT based on my own experience! Read More Read Less

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Anonymous | 75 or over | Female | On medication for 1 to less than 2 years | Patient
7/16/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 2.7
Effectiveness
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Had first shot in October of 2022 and second in April of 2023. Not evaluated yet as bone scan not due until March of 2024. Inherited osteoporosis and osteoarthritis. Had basically no untoward subjective symptoms. Doctors said patients had no bad side effects when I mentioned negative comments I had readl. So I stupidly took the shot fearing if I broke a hip they would just say, "You should have taken the Prolia." Have pain in left ankle and tibia plus lower lumbar area....never had this before. Plus "tired" isn't an adequate word to describe how I feel. Obviously old age is a facet here, but I feel really half dead half of the time. I am due for shot #3 in October. I will get it as the problems associated with quitting appear to be almost worse. I wish I had been born into a better gene pool!Read More Read Less

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Janet Rodriguez | 55-64 | Female | On medication for 6 months to less than 1 year | Patient
7/13/2023
Condition: Osteoporosis
Overall rating 1.0
Effectiveness
Ease of Use
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Before I had Prolia injection back pain was not that bad, after the injection the pain was unbearable as well as constant headaches, jaw pain, muscle pain, my immune system went down, vitamin D and kidney function went down too. Also developed skin rash. I DO NOT recommend Prolia injection not even to my worst enemy, Prolia is poison to the human body.

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Susan | 55-64 | Female | On medication for 2 to less than 5 years | Patient
7/13/2023
Condition: Other
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

This drug gave me cancer. A disaster. I am going to die. The number one reason why women dropped out of the clinical test was they got cancer. It is poison. Shame on the fda for keeping it on the market.

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Jayne | Female | Patient
6/29/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I was put on Forteo for two years self injected. No problems with this treatment. Then we started treatment with Prolia. I had no problems in a 9 year treatment. The treatment is intended to keep your bones stable and these treatments held me to the same level as when I was first diagnosed. I had a foot fracture due to a fall. No other fractures My bones were so bad I was told at age 57 my bones were 15 years older than my real age. Year 10 it changed. I had a reaction to the Prolia. Keeping in mind we can react at any point in our lives to drugs that we never had any issues with. My reaction was rare. Long story short I met with an allergist and he said definitely a Prolia reaction. My symptoms was in the mouth and throat down.. I felt a scratchy throat within a couple hours after the injection which turned into blisters in the throat and down the esophagus. My tongue swelled but just to a fat felling. I had blisters in the throat and down the esophagus. my ENT use the tube and spent a lot of time thru the nasal and Dow. When she finished she said it was nothing she had ever seen. Blisters down to the glottis. Steroids were used, anti fungal meds for just maybe that’s the problem. I had a PET screening for a spot on my lung that was possibly cancer but also could be an infection. We waited 6 weeks had another CT and the spot was resolving. My primary and I were both suspicious that the spot was a blister. She had put me on a Zpak to help if it was an infection. I am pre diabetic and was doing light machine resistance and I ended up with a T-7 compression fracture and had a repair this week. My last injection was September of 2022. I still have issues with No one knows what I should do for treatment. So…today I would say take what you can tolerate. There seems to be a lot of negative information but I have no treatment at this point and I’m afraid I’m going to be crippled up bc of no treatments. If you have one fracture in your spine you will take anything after that to avoid fractures. The pain is incredibly intense and it took 6 weeks to get a repair. So just saying my reaction is not common and probably one of a first bc no ne has seen it before. The medication is to keep your bones where it is. You don’t want them getting worse with no treatment. Good luck to each of you that read this and ask for more information and understanding. It’s very painful to start having spine fractures and have weight restrictions of 8-10 pounds, try not to bend, try not to use your arms above your head reaching. When you can’t pick up your grandkids it breaks your heart. Read More Read Less

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Janet Rodriguex | 55-64 | Female | On medication for 1 to 6 months | Patient
5/19/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

My back pain is worst than ever, cholesterol went way up, immune system decline, muscle and joint pain, jaw pain, lack of appetite, rarely thirsty. This Prolia injection is bad, bad, bad .

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Pami | 65-74 | Female | On medication for 1 to less than 2 years | Patient
5/17/2023
Condition: Osteoporosis
Overall rating 5.0
Effectiveness
Ease of Use
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I had my first Prolia shot March 2022. It was following 2 years of Reclast which was not helping. My bone scan February 2022 results were -2.5 right hip, -2.4 left hip and -4.1 lumbar spine. After my second Prolia shot September 2022, I felt less pain in my back. A dexascan taken February 2023 results were -2.5 right hip, -2.2 left hip and -3.6 lumbar spine. I had my 3rd shot in March. Prolia has worked for me so far. I have 2 neighbors on Prolia and they have not had any adverse reactions.

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Patricia Kuenne | 65-74 | On medication for 6 months to less than 1 year | Patient
3/29/2023
Condition: osteoporosis in postmenopausal woman at high risk for fracture
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

after first injection my nose ran constantly but thought was allergy related. After second injection I lost control of bowels after I ate, it went right thru me with no control and problem is chronic now. 4 months b4 3rd injections I had a bad cough, ex-ray showed my lungs were scarred and read that Prolia can cause this. I was told it was quality of life now, it just gets worse. I have never been around asbestos in my life and usually happens to men in roofing business. I should have looked at reviews instead of listening to my MD. DO NOT TAKE THIS DRUG, IT IS DANGEROUSRead More Read Less

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