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3.7 Overall Rating

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Most voted positive review

16 People found this comment helpful

I've been on this prescription for about a week and a half now. Switched over from bupropion sr. & effexor at the same time. Coming off effexor and surprising not 1 side effect. effexor was decreasing my libido and not sure if coming off effexor or going on aplenzin (or both) but my libido is coming back and the depression has lifted for the most part. Hoping that it only gets better ~ Surprised...

Most voted negative review

13 People found this comment helpful

Do NOT take this poison! It is a high-grade amphetamine. Don't let any doctor lie to you about it. I took it 5 years and have been off it 3 years, taken off this poison by a nonAmerican doctor who doesn't buy into the "give-a-pill" theory of medicine. Wellbutrin has changed my brain permanently. I was never angry before. Now I live every day very angry. My life is hell filled with anger. This medi...

Shared reviews and ratings

Speechless | 55-64 | On medication for 1 to 6 months | Patient
1/20/2020
Condition: Depression
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I was switched from Wellbutrin to Aplenzin 522mg per day. I noticed some disturbing side effects in a two week period. I don't feel dizzy, I feel off balance and have to hold on to things to keep my balance. I also started having severe nausea that Zofran and Phenergan didn't even start to help me. My worst symptom has been an irregularity in my speech pattern. I hesitate and pause between my words. I know what I want to say it is just very difficult to get the words out. Nausea is a little better during the day but all my symptoms get worse in the evening and night. Has anyone else had difficulties with speech while on this medicine? The speech difficulties have been going on for almost 4 weeks. The other symptoms have been gradually getting worse over the past month and a half. I am seeing a Neurologist and he doesn't know why I am having such terrible speech difficulties. I would really like to know if anyone else has had these symptoms?Read More Read Less

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mamataz | 55-64 | On medication for 6 months to less than 1 year | Patient
5/12/2019
Condition: Major Depressive Disorder
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

As I titrated up, I got very serious side effects, increased anxiety, agitation and tremors. Increased depression and suicidal effect. Be very careful of this drug and check drug interactions.

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aajaa | 55-64 | Female | On medication for 6 months to less than 1 year | Patient
2/27/2019
Condition: Bipolar Depression
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I've been taking this drug for 6 months. After the ramp-up to 522mg, I became slightly manic and agitated. Reduced dosage to 348, and it's working great. I'm having some sleep problems, but that could be attributed to other things. The only way I can afford this is by my doc providing samples. I have more energy and focus than I've had in years.

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Heather | 25-34 | On medication for 1 to 6 months | Patient
12/11/2015
Condition: Depression
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

I've been slowing increasing dose of Aplenzin over last 3 months to 522mg. I just read a review about severe acne as possible side effect

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JonathanT | 45-54 | Male | On medication for 2 to less than 5 years | Patient
6/18/2015
Condition: Depression
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I had been on 450 mg Wellbutrin daily for years with so-so results. My doc gave me a 30 day supply of 522 mg Aplenzin to try and it was as if someone turned the lights on. After only ONE day I noticed an immediate feeling of well-being that was bordering on euphoria without having to worry about the crash & burn. Although I am unable to take a daytime nap, I have no trouble sleeping at night. I am worried about the price - when I started it cost $1500/month and now it is almost $3000/month... this seems very high, but then again, nothing has ever worked as well as Aplenzin. I am afraid that my insurance company will decide that it is not worth the cost to have one of their patients feeling so good. While my sex drive is hampered a bit (but I also have low-T) and I may have put on a few extra pounds, I hardly consider those side effects troublesome enough to stop the Aplenzin. This is truly a miracle drug.Read More Read Less

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iliveinmyinbox | 45-54 | Female | On medication for 5 to less than 10 years | Patient
5/11/2013
Condition: Depression
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

Do NOT take this poison! It is a high-grade amphetamine. Don't let any doctor lie to you about it. I took it 5 years and have been off it 3 years, taken off this poison by a nonAmerican doctor who doesn't buy into the "give-a-pill" theory of medicine. Wellbutrin has changed my brain permanently. I was never angry before. Now I live every day very angry. My life is hell filled with anger. This medication is poison. Please, don't do this to your life and your brain. Run very far. I would give anything not to have taken this poison. I'm very sure my Medicare paid for the mags on my first doctor's Porsche. Eat right and exercise. Do not surrender to the "medicines" Rx companies give you. They don't care what it does to your brain. They only care about their profits. PLEASE, PLEASE take this seriously. Or you will be awakening every morning irrationally filled with hate and anger when you never were before. That's where I'm at now. I don't know when it will end. If ever.Read More Read Less

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gigi | 55-64 | Female | On medication for 1 to 6 months | Patient
12/18/2012
Condition: Depression
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

Extremely tired, ringing in ears

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Pnwrighteous | 45-54 | Female | On medication for 1 to less than 2 years | Patient
6/30/2012
Condition: Major Depressive Disorder
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

My shrink switched me to 522 mg of Aplenzin from 300 ml wellbutrin and 60 mg cymbalta. I've been on it for a year. And I've never felt better. I'm finally losing weight and have a sex drive again. I've had major clinical depression for 26 yrs now. This is the best medicine I've taken so far.

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lyksherry8 | 65-74 | Female | On medication for less than 1 month | Patient
4/4/2012
Condition: Depression
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

I am having Nausia, headaches, dizzy, eyesight blurry, heat

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klinkaz | 25-34 | Female | On medication for 1 to less than 2 years | Patient
3/2/2012
Condition: Depression
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I switched from Prozac to this drug a little over a year ago. I was on Prozac for about 10 years, but wasn't happy with the lack of libido. I have been taking 174 mg of Aplenzin 4 days a week and 348mg three days a week for a little over a year now. I have never felt better. Unfortunately, I think it's causing severe acne. About 3 months after I started taking it, I started getting terrible breakouts. I'm 32 and have never had acne problems. I have spent the last year battling cystic acne and literally trying every single treatment/remedy I can think of. All my hormone levels are normal, so I know that isn't the cause. I've started analyzing all my supplements and medications to see if there is a link. I'm just realizing that Aplenzin may be the primary cause (given the timeline). Unfortunately, I haven't seen it listed among the side effects and was curious if I'm the only one having this problem. possible.Read More Read Less

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DWMAH | 55-64 | Male | On medication for 1 to 6 months | Patient
2/7/2012
Condition: Depression
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

Went over to this from Lexapro due to Lexapro side effects getting worse over time. So far so good only one month, generally feel better, more energy, less appetite, no mood swings.

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Anonymous | 65-74 | Male | On medication for 6 months to less than 1 year | Patient
7/12/2011
Condition: Depression
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

seems best formulation ive tried

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Anonymous | 25-34 | Female | On medication for less than 1 month | Patient
5/15/2011
Condition: Other
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

Crap! I took this medication for 3 weeks and my hair started falling out. Every time I ate something I would have severe abdominal cramps. I also had severe headaches and eye pain. Crap! Crap! Crap!

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Anonymous | Female | Patient
2/19/2011
Condition: Other
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

It took awhile to work, but it made a difference in my life. Much better than Wellbutrin.

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Anonymous | 35-44 | Female | On medication for less than 1 month | Patient
1/9/2011
Condition: Depression
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

I have had an increase in hunger that comes on suddenly and strongly. Did not have any decrease of symptoms so far.

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apenzin | 45-54 | Female | Patient
12/9/2010
Condition: Bipolar Depression
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction
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Anonymous | 35-44 | Female | On medication for less than 1 month | Patient
12/8/2010
Condition: Attention Deficit Disorder with Hyperactivity
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I started seeing results in one week!

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B | 75 or over | Female | On medication for 1 to 6 months | Patient
11/29/2010
Condition: Depression
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

Still do not feel 100%

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jennerationb | 25-34 | Female | On medication for 1 to 6 months | Patient
11/19/2010
Condition: Depression
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

I've been on different anti-depressants for about 10 years now. I had recently been on Effexor XR but noticed weight gain and constant trembling in my hands. I switched over to Aplezin about 1 month ago and it's been great. I feel happier than I have in a long time, and I now have to remind myself to eat because I have little to no appetite.

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suzieQ | 55-64 | Female | On medication for 1 to less than 2 years | Patient
9/22/2010
Condition: Bipolar Depression
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

I was switched to Aplenzin last year after Wellbutrin quit working for me. The one side effect that has been increasing month after month is tremors. I am now shaking so much that I have trouble holding things like my cell phone. It is very disturbing and frustrating to have my hands shake so much. It's not just trembling, it's full blown muscle jerking. I can see my hand muscles jumping when I'm driving my car. Looks like I will have to discontinue this drug.I have tried so many other meds I don't know what will happen if I stop taking it.Read More Read Less

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