Levothyroxine/Sodium Polystyrene Sulfonate
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Sodium polystyrene sulfonate may bind to your thyroid hormone in your digestive tract, preventing your body from absorbing your medicine.
What might happen:
A decrease in the beneficial effects of your thyroid medicine may occur.
What you should do about this interaction:
Try to time your medicines so that you take your thyroid medicine at least 4 hours from sodium polystyrene sulfonate.If you experience fatigue, sluggishness, constipation, stiffness, muscle cramps, loss of appetite, weight gain, dry skin, or difficulty in cold weather, contact your doctor.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Synthroid (levothyroxine sodium) US prescribing information. Abbott Laboratories June, 2011.