No monograph available at this time.
Side Effects
What are the most common side effects of rosuvastatin?
The most common side effects of rosuvastatin are listed below. Tell your healthcare provider if you have any of these side effects that bother you.
- Headache
- Nausea
- Muscle aches and pain
- Weakness
- Constipation
- Stomach pain
There may be other side effects of rosuvastatin that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
What are the serious side effects of rosuvastatin?
While less common, the most serious side effects of rosuvastatin are described below, along with what to do if they happen.
Muscle Problems. Rosuvastatin can cause muscle problems, including muscle pain, weakness, and tenderness called myopathy. In some people, the muscle may break down (rhabdomyolysis), which can be serious and rarely lead to kidney damage and death. Stop taking rosuvastatin and get help right away if you have any of the following symptoms of myopathy or rhabdomyolysis.
- Unexplained muscle pain, weakness, or tenderness
- Low energy levels or feeling easily tired, especially with activity
- Dark colored urine
- Fever
- Muscle cramps
- Stomach pain
- Nausea or vomiting
Liver Damage. Liver damage, also called hepatotoxicity, can happen when taking rosuvastatin. Call your healthcare provider right away if you have any of the following symptoms of liver damage.
- Nausea or vomiting
- Stomach or belly pain
- Fever
- Weakness or unusual tiredness
- Itching
- Loss of appetite
- Light colored poop
- Dark colored urine
- Your skin or the whites of your eyes turning yellowish in color (also called jaundice)
Increased Blood Sugar. Rosuvastatin may increase your blood sugar levels. Talk to your healthcare provider about how to maintain healthy blood sugar levels.
Blood and Protein in Urine (Pee). Rosuvastatin may cause you to have protein and blood in your urine. If you develop protein or blood in your urine, talk to your healthcare provider.
Severe Allergic Reactions. Rosuvastatin can cause allergic reactions, which can be serious. Stop taking rosuvastatin and get help right away if you have any of the following symptoms of a serious allergic reaction:
- Breathing problems or wheezing
- Racing heart
- Fever or general ill feeling
- Swollen lymph nodes
- Swelling of the face, lips, mouth, tongue, or throat
- Trouble swallowing or throat tightness
- Itching, skin rash, or pale red bumps on the skin called hives
- Nausea or vomiting
- Dizziness, feeling lightheaded, or fainting
- Stomach cramps
- Joint pain
Precautions
Consult your pharmacist or physician.
Interactions
Does rosuvastatin interact with foods or drinks?
There are no known interactions between rosuvastatin and foods or drinks.
Limit the amount of alcohol you drink while taking rosuvastatin. The risk of liver damage may be increased if you drink significant amounts of alcohol. Tell your healthcare provider if you drink more than 2 glasses of alcohol per day before taking rosuvastatin.
Does rosuvastatin interact with other medicines (drug interactions)?
Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
In particular, make sure that you discuss if you are using any of the following before taking rosuvastatin.
- A medicine used for HIV, AIDS, or Hepatitis C
- Ketoconazole, fluconazole (Diflucan), itraconazole (Sporanox, Tolsura), posaconazole (Noxafil), or voriconazole (Vfend) which are medicines used for fungus infections
- An antacid, which is a medicine used for indigestion and heartburn
- Capmatinib, which is a medicine used to treat a type of lung cancer
- Colchicine, which is commonly used for gout
- Cyclosporine (Gengraf, Neoral, Sandimmune, and others), which is a medicine to suppress your immune system
- Darolutamide, which is a medicine used to treat prostate cancer
- Enasidenib, which is a medicine used to treat a type of blood cancer
- Febuxostat, which is a medicine used to treat high blood levels of uric acid
- Fostamatinib, which is a medicine used to treat low platelet counts
- Niacin or a fibrate such as gemfibrozil (Lopid), fenofibrate (Tricor), or fenofibric acid (Fibricor, Trilipix), which are medicines for high cholesterol
- Regorafenib, which is a medicine used to treat cancer of the colon and rectum
- Tafamidis, which is a medicine used to treat certain heart problems
- Teriflunomide, which is a medicine used to treat multiple sclerosis
- Warfarin (Coumadin, Jantoven), which is a medicine used to treat blood clots
Some other medicines may alter the blood levels of rosuvastatin. Tell your healthcare provider about all medicines that you take or have recently taken.
Does Rosuvastatin CALCIUM interact with other drugs you are taking?
Enter your medication into the WebMD interaction checker Overdose
If someone has overdosed and has serious symptoms such as passing out or trouble breathing , call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Notes
Missed Dose
Consult your pharmacist or physician.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.