If you are:
Only When Necessary:
Absolute Contraindication: LOW MW, POTENTIAL FOR SERIOUS ADVERSE EFFECTS( NEPHROTOXICITY AND HEPATITIS)
An adult over 60:
management or monitoring precaution: Renal-Decreased renal function predisposes to higher risk of nephrotoxicity. Dose interval adjustment for CrCL<50 mL/min.
Giving Adefovir DIPIVOXIL to a child under 12:
management or monitoring precaution: Not recommended age less than 12 years. No demonstrated efficacy.