If you are:
Only When Necessary: NON-TERATOGENIC COMPLICATIONS (RESP, GI,CNS) WITH EXPOSURE DURING 3RD TRIMESTER
Precaution: NO KNOWN INFANT ADV EFFECTS WITH SHORT TERM TX, LONG TERM CNS EFFECTS UNKNOWN
An adult over 60:
management or monitoring precaution: Hepatic-May need to adjust dose especially in combination with renal impairment. Renal-Decrease initial dose by 25% in mild to moderate renal impairment. Endocrine-Increased risk of SIADH and hyponatremia resulting in an increased risk of falls. Cardiovascular-Elderly at increased risk for orthostatic hypotension.
Giving venlafaxine HCL ER to a child under 12:
Severe Precaution: Suicide precaution. Slowed growth rate, weight loss. Monitor height and weight, blood pressure, cholesterol. Risk of sustained hypertension, hypercholesterolemia, agitation. No safety and efficacy done beyond 6 months of treatment.
Severe Precaution: No safety and efficacy. Possible suicide risk, reduced growth rate, appetite loss.