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    Zofran

    precautions

    What should I know regarding pregnancy, nursing and administering Zofran to children or the elderly?

    If you are:

    Pregnant:

    FDB Only When Necessary: INSUFFICIENT HUMAN DATA AVAILABLE; NO DEVELOPMENTAL TOXICITY SEEN IN ANIMALS

    Nursing:

    Precaution: INSUFFICIENT DATA AVAILABLE

    An adult over 60:

    management or monitoring precaution: Cardiovascular- Limit initial IV doses to no more than 8 mg for age>74 and no more than 16 mg for ages 66-74. Subsequent doses must not exceed 8 mg and given no sooner than 4-8 hours later. Infuse over a minimum of 15 min. The elderly are more prone to QT prolongation due to multiple meds and iatrogenic hypokalemia, hypomagnesemia; correct electrolytes before giving oral or IV ondansetron. Neuro/Psych-The elderly may be more prone to extrapyramidal reactions associated with IV doses.

    Giving Zofran to a child under 12:

    Severe Precaution: Limited information age < 30 days. Longer half-life in infants. Monitor closely.

    Severe Precaution: Longer half-life in age < 4 months. Monitor closely.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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