If you are:
Only When Necessary: INSUFFICIENT HUMAN DATA AVAILABLE; ADVERSE EFFECTS SEEN IN ANIMALS AT >6 X MRHD.
Absolute Contraindication: SERIOUS ADVERSE EFFECTS IN 2 CASES: RESPIRATORY DEPRESSION,FEEDING DIFFICULTY
An adult over 60:
Contraindication: Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Even topical preparations have led to anticholinergic toxicity in the elderly. Cardiovascular-May cause orthostatic hypotension at higher doses. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Giving adapin-capsule to a child under 12:
Severe Precaution: Possible increased suicidal ideation & attempt in pediatrics with major depression. Not recommended for use in pediatrics age < 12 years.