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Drugs & Medications

tbo-filgrastim subcutaneous

COMMON BRAND NAME(S): Granix

GENERIC NAME(S): TBO-FILGRASTIM

Uses

This medication is given to people receiving certain chemotherapy drugs that cause a decrease in white blood cells. When white blood cell counts are very low, it increases the risk of serious infections. Tbo-filgrastim belongs to a class of drugs known as granulocyte colony stimulating factors (G-CSF). It works by stimulating your bone marrow to make more white blood cells. This effect helps lessen the risk of serious infections after chemotherapy.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This medication may also be used to increase low white blood cell counts caused by certain other conditions (such as severe chronic neutropenia).

How to use tbo-filgrastim subcutaneous

Read the Patient Information Leaflet provided by your pharmacist before you start using tbo-filgrastim and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection under the skin by a health care professional, usually once a day, starting at least 24 hours after you receive chemotherapy. The dosage is based on your medical condition, weight, and response to treatment.

Use this medication regularly to get the most benefit from it. Keep all medical and laboratory appointments.

Side Effects

Bone pain may occur. Taking a non-aspirin pain reliever such as acetaminophen may help with this pain. Ask your doctor or pharmacist for more details. Injection site redness, swelling, itching, lumps, or bruising may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Get medical help right away if you have any very serious side effects, including: breathing problems (such as trouble breathing, shortness of breath, fast breathing), unusual decrease in urinating, tiredness, swelling/puffiness of the body.

Rarely, serious (possibly fatal) damage to the spleen may occur. Get medical help right away if you develop stomach/abdominal pain and/or shoulder pain.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using tbo-filgrastim, tell your doctor or pharmacist if you are allergic to it; or to filgrastim/pegfilgrastim; or to other medications made in a similar manner (biotechnology-produced proteins using E. coli); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: sickle cell disease, spleen problems.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Tbo-filgrastim is very similar to filgrastim and pegfilgrastim. Do not use filgrastim or pegfilgrastim while using tbo-filgrastim.

This medication may interfere with certain laboratory tests (such as bone scans/imaging tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Laboratory and/or medical tests (such as complete blood counts) must be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule.

Storage

Not applicable. This medication is given in a hospital or clinic and will not be stored at home.

Information last revised April 2014. Copyright(c) 2014 First Databank, Inc.

Images

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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