This medication is given to people receiving certain chemotherapy drugs that cause a decrease in white blood cells. When white blood cell counts are very low, it increases the risk of serious infections. Tbo-filgrastim belongs to a class of drugs known as granulocyte colony stimulating factors (G-CSF). It works by stimulating your bone marrow to make more white blood cells. This effect helps lessen the risk of serious infections after chemotherapy.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This medication may also be used to increase low white blood cell counts caused by certain other conditions (such as severe chronic neutropenia).
Read the Patient Information Leaflet provided by your pharmacist before you start using tbo-filgrastim and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
This medication is given by injection under the skin as directed by your doctor, usually once a day, starting at least 24 hours after you receive chemotherapy. The dosage is based on your medical condition, weight, and response to treatment. Follow your doctor's instructions carefully.
If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the Instructions for Use Leaflet. Remove the medication from the refrigerator 30 minutes before you inject it to allow it to reach room temperature. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Do not shake this medication. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Never inject tbo-filgrastim into skin that is tender, red, bruised, or hard, or has scars or stretch marks. Ask your doctor, pharmacist or nurse any questions you may have about how to give yourself tbo-filgrastim. Learn how to properly dispose of used syringes, needles, and any unused medication. Never reuse needles or syringes.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day. Keep all medical and laboratory appointments.
Bone pain may occur. Taking a non-aspirin pain reliever such as acetaminophen may help with this pain. Ask your doctor or pharmacist for more details. Injection site redness, swelling, itching, lumps, or bruising may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: pink/bloody urine.
Get medical help right away if you have any very serious side effects, including: breathing problems (such as trouble breathing, shortness of breath, fast breathing), unusual decrease in urination, unusual tiredness, swelling/puffiness of the body.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before using tbo-filgrastim, tell your doctor or pharmacist if you are allergic to it; or to filgrastim, filgrastim-sndz, or pegfilgrastim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: sickle cell disease, spleen problems.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Tbo-filgrastim is very similar to filgrastim, filgrastim-sndz and pegfilgrastim. Do not use filgrastim, filgrastim-sndz, or pegfilgrastim while using tbo-filgrastim.
This medication may interfere with certain laboratory tests (such as bone scans/imaging tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Do not share this medication with others.
Laboratory and/or medical tests (such as complete blood count, kidney function) must be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule.
Store in the refrigerator. Keep the medication in the original carton to protect from light. Avoid shaking the medication. This medication may also be stored at room temperature for up to 5 days. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised October 2015. Copyright(c) 2015 First Databank, Inc.
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