Accolate precautions What should I know regarding pregnancy, nursing and administering Accolate to children or the elderly?If you are: Pregnant: Possibly Safe Nursing: Absolute Contraindication: NOT RECOMMENDED. TUMORIGENIC IN MOUSE/RAT STUDIES. An adult over 60: Precaution: ELDERLY MAY SHOW LESS IMPROVEMENT IN EFFICACY MEASURES. Giving Accolate to a child under 12: Warning: SAFETY AND EFFICACY NOT ESTABLISHED IN PEDIATRICS AGE < 5 YEARS. Warning: MONITOR FOR NEUROPSYCHIATRIC AND/OR BEHAVIORAL CHANGES.